Back in the days before OS X, the number of viruses which attacked Macintosh users totalled somewhere between about 60 and 80. Today, the number of viruses actively attacking OS X users is none. However, this doesn't mean we should get complacent about checking incoming email attachments or web downloads.
ClamXav is a free virus scanner for Mac OS X. It uses the very popular ClamAV open source antivirus engine as a back end and has the ability to detect both Windows and Mac threats.
ClamXav can be setup up as passive or active: scan only the files you tell it to or your entire hard drive, whichever you prefer; you can also choose to activate Sentry to monitor your hard drive and scan new files as they arrive.
View In iTunes - ClamXav: The Free Anti-Virus Solution for Mac OS X